[Allergy to cow's milk proteins].

نویسنده

  • J L Eseverri Asín
چکیده

Cuvinte cheie: alergie, proteine lapte vacă, toleranţa orală Rezumat: Alergia la proteinele din laptele de vacă este definită ca reacţia imunologică, mediată sau nemediată IgE, la proteinele din laptele de vacă. Afectează populaţia pediatrică în primii 2 ani de viaţă, după această vârstă instalându-se toleranţa la proteinele din laptele de vacă. Sistemul imun intestinal este răspunzator de iniţierea reacţiei alergice intestinale prin stimularea secreţiei de IgAs şi iniţierea toleranţei orale. Toleranţa orală indusă reprezintă strategia de prevenire a reacţiei alergice intestinale. Prezenţa epitopilor legaţi de proteinele din laptele de vacă măresc capacitatea de recunoaştere antigenică şi constituie baza imunoterapiei orale. Simptomatologia este nespecifică. Diagnosticul pozitiv se bazează pe datele furnizate de istoricul familial, dieta de eliminare, testul de provocare şi dozarea IgE totale şi specifice. Tratamentul constă în administrarea de formule terapeutice. Alimentaţia naturală rămâne gold-standardul de prevenire a alergiei la proteinele din laptele de vacă. Prognosticul este favorabil, cu remisiune după vârsta de 3 ani.

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عنوان ژورنال:
  • Anales espanoles de pediatria

دوره 29 Suppl 33  شماره 

صفحات  -

تاریخ انتشار 1988